Vacuum Concentration: Process, Applications & Pump Requirements

Vacuum concentration is a crucial technique in laboratory sample preparation, allowing for efficient solvent removal while preserving sample integrity. The concentration process is widely used in research and industry applications where precision and reproducibility are essential. Selecting the right vacuum pump and system ensures optimal evaporation control, preventing sample loss and improving overall lab efficiency.

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What is Vacuum Concentration?

Vacuum concentration is a laboratory technique used to remove solvents from samples through controlled evaporation. By applying vacuum pressure, the boiling point of the solvent is lowered, allowing for efficient solvent removal at reduced temperatures. This method is widely used in applications where preserving sample integrity is critical, as it minimizes thermal degradation and enhances reproducibility.

By carefully considering your specific application needs and the features of available pumps, you can find a vacuum pump that will provide reliable and efficient performance for years to come. If you have any questions, reach out to our customer service at : 1-888-522- | :  

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Protein extraction, purification, and cleanup methods frequently produce dilute samples of target biomolecules in buffer matrices incompatible with downstream applications. Pierce protein concentrators are disposable ultrafiltration centrifugal devices used to concentrate, desalt, and buffer exchange biological samples, such as proteins and nucleic acids, readying them for downstream applications with minimal sample handling. Pierce protein concentrators are available in four sizes (0.5, 6, 20, and 100 mL) and offer pH compatibility over a broad pH range (1–9).

The Nanocon™ Crossflow Concentrator is an innovative solution for exosome, lipid nanoparticle (LNP), and virus enrichment. The 30 nM pore size PE membrane is perfect for nanosized particles, and it fits conveniently in a 250 mL centrifuge adapter.

For larger volume sizes, Pierce crossflow filtration cassettes are designed for high purity and recovery of peptides, proteins, and virus/viral particles. They are used to concentrate large supernatant volumes (0.5 L–6 L). Additional accessories are available for use with the crossflow filtration cassettes.

If you want to learn more, please visit our website Modular type Ion Chromatography.