1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic Acid Pinacol Ester (CAS 903550-26-5): Product Overview, Research Uses, and Sourcing Guide

1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester, CAS 903550-26-5, is a pyrazole-based boronic ester used as a building block in synthetic chemistry research. It combines a pyrazole ring, an N-substituted tetrahydropyranyl group, and a pinacol boronate functionality that can be considered for boron-mediated carbon–carbon bond formation, including Suzuki–Miyaura coupling routes. Its molecular formula is C₁₄H₂₃BN₂O₃, and its molecular weight is approximately 278.16 g/mol. Below, we explain how to assess its research fit, evaluate product documentation, and request a suitable supply offer from Maison Chemical.

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Key Takeaways

• This compound is a pyrazole building block bearing a pinacol boronate ester and an N-tetrahydropyranyl substituent.
• Its formula, C₁₄H₂₃BN₂O₃, represents one boron atom per molecule; the molecular weight is approximately 278.16 g/mol.
• Research suitability depends on the intended coupling partner, reaction conditions, and compatibility of the N-substituent with the planned synthesis.
• Before ordering, confirm the requested quantity, purity specification, analytical documentation, packaging, and delivery terms with the supplier.

Who This Guide Is For

This guide is intended for medicinal and organic chemistry researchers, process-development teams, procurement specialists, and distributors evaluating CAS 903550-26-5. It is particularly relevant when a project calls for a pyrazole-containing intermediate with a boronate handle for subsequent synthetic elaboration. The guide focuses on research and sourcing considerations rather than prescribing a specific reaction or guaranteeing a particular result. Buyers should assess the material against their own route, analytical requirements, and internal handling procedures.

Product Concept and Research Uses

Structure and Functional Role

The molecule contains a pyrazole heterocycle, a tetrahydropyran-2-yl group attached to a ring nitrogen, and a boronic acid pinacol ester at the pyrazole 5-position. The pinacol ester is a protected boron-containing functionality commonly used as a coupling handle in synthetic chemistry. In a planned route, the pyrazole fragment may be introduced to another molecular fragment through a suitable cross-coupling transformation. Whether this compound performs well in a specific reaction depends on the partner, catalyst system, solvent, base, temperature, and other experimental variables.

The N-substituent is also relevant to route design. It may be intended to control or modify the reactivity of the pyrazole nitrogen during selected synthetic steps, but its compatibility and eventual removal must be assessed for the target structure. Deprotection conditions are substrate-dependent and should be selected and tested by the research team. The presence of a tetrahydropyranyl group should not be treated as proof that a particular deprotection protocol will work without affecting other functional groups.

Where It May Fit in a Research Route

Researchers may evaluate CAS 903550-26-5 when designing pyrazole-containing compounds, exploring heterocycle diversification, or screening routes that use organoboron coupling partners. It may be useful as a starting intermediate where the desired product requires a new carbon–carbon bond at the pyrazole 5-position. It is not a finished pharmaceutical ingredient, and the compound’s availability does not imply regulatory approval or suitability for human use. Any intended application should be supported by appropriate laboratory evaluation and material documentation.

Specification and Material Options to Confirm

For initial identification, compare the product name and CAS number on the quotation, label, and supporting documents. The molecular formula is C₁₄H₂₃BN₂O₃, the approximate molecular weight is 278.16 g/mol, and each molecule contains one boron atom. These values are useful identity checks, but they do not establish a batch’s purity, water content, or suitability for a particular reaction. Request the current batch documentation and review it against your project’s acceptance criteria.

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How to Match the Compound to Your Application

Use a Route-Based Selection Framework

1. Define the synthetic objective. Identify the bond to be formed and confirm that a pyrazole-5-boronate is appropriate for the proposed route.
2. Review functional-group compatibility. Consider whether the N-tetrahydropyranyl substituent and other groups in the planned reaction sequence can tolerate the intended conditions.
3. Set material criteria. Specify the purity target, analytical documentation, quantity, and any packaging or handling requirements before requesting a quote.
4. Plan verification. Decide how your team will check identity and quality on receipt, using its established analytical and quality procedures.
5. Confirm commercial details. Obtain written confirmation of price, minimum order quantity, lead time, shipping arrangement, and document availability for the requested batch.

This route-first approach helps distinguish a technically suitable intermediate from one that is merely similar by name. A boronate may be appropriate for a proposed coupling, but the outcome can depend on conditions and substrate behavior that cannot be inferred from the product name alone. Where route compatibility is uncertain, a small-scale evaluation may be appropriate if the supplier can offer a suitable quantity. Any such evaluation should follow the buyer’s laboratory safety and approval procedures.

Pricing, MOQ, and Lead-Time Considerations

Pricing for a specialty chemical can vary with requested quantity, batch availability, specification, packaging, and shipping destination. Minimum order quantity and lead time should therefore be confirmed for the specific inquiry rather than assumed from a general product listing. A larger requested amount does not by itself establish a lower unit price, and no fixed delivery schedule should be relied upon until it is confirmed in writing. For planning, provide the required quantity and target delivery window when requesting a quotation.

Buyers should also clarify whether the offer refers to a currently available batch or a supply subject to production or procurement arrangements. Ask which quality documents can accompany the shipment and whether the stated specification applies to the offered lot. If your organization requires special documentation, packaging, or import information, raise these points before order confirmation. Early alignment can reduce avoidable delays during purchasing and material qualification.

Supplier Evaluation Checklist

• Does the quotation identify the exact compound and CAS number?
• Are the offered specification and available batch documents clearly stated?
• Can the supplier confirm the requested quantity, packaging, and estimated lead time?
• Are shipping terms and any destination-specific requirements discussed before dispatch?
• Can questions about product documentation and supply coordination be addressed before purchase?

Maison Chemical supports B2B inquiries for specialty chemicals and pharmaceutical intermediates, including requests for this pyrazole boronate. For CAS 903550-26-5, buyers can share the desired quantity, target specification, destination, and documentation needs so the supply team can respond to the actual purchasing scope. Availability, commercial terms, and document options should be confirmed for each order. This approach gives both parties a clear basis for assessing whether the offer fits the project.

Conclusion and Next Steps

CAS 903550-26-5 is a pyrazole-based pinacol boronate that researchers may consider as a coupling intermediate when their route calls for a pyrazole fragment bearing a boron handle. Its identifying data include the formula C₁₄H₂₃BN₂O₃, a molecular weight of approximately 278.16 g/mol, and one boron atom per molecule. These facts help identify the structure, but route compatibility and batch quality require project-specific evaluation. To proceed, define your technical specification, request batch documentation, and confirm price, MOQ, lead time, and shipping details with Maison Chemical before placing an order.

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